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CCR10 antagonist 1
CAS No. 1191031-97-6
CCR10 antagonist 1( —— )
Catalog No. M10657 CAS No. 1191031-97-6
CCR10 antagonist 1 is a potent, selective CCR10 antagonist with IC50 of 690 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameCCR10 antagonist 1
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NoteResearch use only, not for human use.
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Brief DescriptionCCR10 antagonist 1 is a potent, selective CCR10 antagonist with IC50 of 690 nM.
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DescriptionCCR10 antagonist 1 is a potent, selective CCR10 antagonist with IC50 of 690 nM; demonstrates functional CCR1 antagonism by inhibiting the CCL27 dependent chemotaxis of Ba/F3 cells stably transfected with human CCR10 with an IC50 of 53 nM, exhibits no antagonism of murine CCL27 dependent Ca2+ flux in CHO-K cells stably transfected with murine CCR10 at 20 uM.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetChemokine Receptor
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RecptorChemokine Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1191031-97-6
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Formula Weight519.398
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Molecular FormulaC19H24Cl2N6O5S
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name4-amino-3,5-dichloro-N-(1-(4-methylpiperidin-1-yl)-4-(2-nitro-1H-imidazol-1-yl)-1-oxobutan-2-yl)benzenesulfonamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Abeywardane A, et al. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5277-5283.
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